Psychedelics show promise for mental health disorders

Psychedelics Show Promise for Mental Health Disorders

Psychedelics Show Promise for Mental Health Disorders Until recently, psychedelics, specifically psilocin from mushrooms and lysergic acid diethylamide (LSD), were limited to recreational use with no medicinal benefit. Currently, psychedelics are showing promise in clinical trials as therapeutic strategies for mental health disorders. While scientists understand the serotonergic modulation these drugs elicit in the brain […]

Promising Results Shown for CRISPR in Clinical Studies

Promising Results Shown for CRISPR

Promising Results Shown for CRISPR CRISPR has shown promising results in preliminary clinical studies to correct sickle cell disease and treat blindness, transthyretin amyloidosis, and hereditary angioedema. A new study in collaboration with University College London and Great Ormond Street Hospital for Children investigated the potential feasibility of base-edited CD7-targeted chimeric antigen receptor (BE-CAR7) T […]

The US FDA no longer requires animal testing for drug approval

The US FDA no longer requires animal testing for drug approval

The US FDA no longer requires animal testing for drug approval. For over 80 years, the FDA has required extensive animal testing to approve drugs before being brought to the public market. In late December 2022, Joe Biden signed into law the Consolidated Appropriation Act that eliminated the need for animal testing before a drug […]

NGM’s closely-watched NASH prospect flops, cutting shares in half and spurring R&D rethink

A phase 2b trial of NGM Biopharmaceuticals’ aldafermin in nonalcoholic steatohepatitis (NASH) has missed its primary endpoint, sending shares in the biotech tumbling. NGM has pulled plans to enter phase 3 in light of the midstage failure of the FGF19 analog. California-based NGM ramped up expectations for aldafermin last year when it delivered midphase data linking […]


December 10, 2020 – An historic alliance of life sciences and healthcare organizations seeks to accelerate the broad adoption of patient-focused, decentralized clinical trials and research. The Decentralized Trials & Research Alliance (DTRA) plans to unite stakeholders, including healthcare companies, regulators, patient groups and research organizations, with a mission to make clinical trial participation widely accessible […]

Japan Grants Patent to Brainstorm Covering Technique for NurOwn

The Japan Patent Office has granted a patent to Brainstorm Cell Therapeutics covering the proprietary technique that generates the company’s cell-based therapy NurOwn from mesenchymal stem cells (MSCs). Through this technique, researchers can harness MSCs directly from a patient and mature them into cells that produce high levels of neurotrophic factors, which are compounds that […]

Novartis presents data at ACTRIMS-ECTRIMS for Kesimpta® (ofatumumab) in newly diagnosed treatment-naïve adults with relapsing multiple sclerosis

New post hoc data from Phase III ASCLEPIOS trials showed newly diagnosed, treatment-naïve patients experienced reductions in annualized relapse rates, MRI lesion activity and reductions in time to disability worsening when treated with Kesimpta vs teriflunomide(1) Additional safety data in over 1,800 patients who continued Kesimpta treatment or switched therapy from previous studies reinforce the […]