Closed-loop Neuromodulation in an Individual with Treatment-Resistant Depression Meriam-Webster defines depression as feelings of severe despondency and dejection, a severe medical condition in which a person feels very sad, hopeless, and unimportant and is often unable to live normally. In the end, the feelings of dejection and a hopeless existence leads many down the dark […]
L-SOMA Gastric Auto-Injectors The majority of the world’s population very rarely thinks of the route of administration needed to maximize the efficiency of a drug. You have a headache, swallow a Tylenol, allergies intranasal delivery “snort” Flonase, having an asthma attack inhale Albuterol, or you accidentally bit into a peanut butter cookie thinking it was […]
CRISPR Engineered Bioimplants Inflammation is a natural and necessary biological process that helps with wound healing as well as combating infection. However, the adage “too much of a good thing” is as relevant in a biological system as in our day-to-day lives. Rheumatoid arthritis (RA) is a chronic inflammatory disease state that primarily affects the […]
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis The future is now … “clustered regularly interspaced short palindromic repeats” and associated Cas9 endonuclease aka CRISPR-Cas9 had its inception in 2012 and a Nobel prize awarded in 2020. CRISPR is a powerful gene-editing technique first discovered in bacteria and adapted for permanent human gene knockout. While […]
Bacteria are fascinating little machines. In the past century, we have harnessed the power of bacteria to produce antibiotics, recombinant drugs, and food. We as humans have evolved and lived, sometimes symbiotically, with bacteria, i.e., in the case of intracellular mitochondria and cellular energy production. This same symbiosis is seen with the bacteria that line […]
In June, the FDA approved Wegovy for chronic weight management. This subcutaneous injection is the first approved drug for chronic weight management in adults with a high BMI and general obesity since 2014. With 70% of American adults being overweight or obese, there certainly seems to be room for new drug entrants to this growing […]
Birth control is a universal term that encompasses everything from a physical barrier to the chemical inhibition of ovulation. The most common form of contraception, according to the CDC, is female sterilization. Excluding sterilization, the second and third most common forms of birth control are oral contraceptive pills and long-acting reversible contraceptives. The commonality of […]
AstraZeneca’s mega $39 billion takeover of Alexion Pharmaceuticals has come to a close, delivering the British pharma a lucrative portfolio of immunology medicines and a towering presence in rare diseases. AZ on Wednesday announced the completion of its Alexion acquisition, a week after securing a pivotal nod from the U.K.’s Competition and Markets Authority (CMA). Industry watchers were concerned […]
Amazon has already changed the way we shop and filled our homes with “smart” gadgets, and now, the tech giant is looking to change the way we manage our health, both in the face of a pandemic and beyond. Amid the launch of its own wellness-tracking smartwatch and the expansion of the Amazon Care telehealth service, […]
Provention was flying high on Tuesday when an FDA advisory panel seemed to back the efficacy of its diabetes prevention drug, even after the agency flagged some issues with the data package supporting the therapy’s application a month earlier. But the company is not out of the woods yet, with the final vote only narrowly […]
