Intracellular delivery of protein drugs

Intracellular Delivery of Protein Drugs

Intracellular Delivery of Protein Drugs Intracellular protein delivery is a daunting task that is near impossible due to the size and surface charge of proteins. However, protein macromolecule delivery is used in numerous disease states, such as monoclonal antibody therapeutics for cancer, autoimmune diseases, or asthma as well as the delivery of recombinant insulin to […]

L-SOMA Gastric Auto-Injectors Image

L-SOMA Gastric Auto-Injectors

L-SOMA Gastric Auto-Injectors The majority of the world’s population very rarely thinks of the route of administration needed to maximize the efficiency of a drug. You have a headache, swallow a Tylenol, allergies intranasal delivery “snort” Flonase, having an asthma attack inhale Albuterol, or you accidentally bit into a peanut butter cookie thinking it was […]

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis

CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis The future is now … “clustered regularly interspaced short palindromic repeats” and associated Cas9 endonuclease aka CRISPR-Cas9 had its inception in 2012 and a Nobel prize awarded in 2020. CRISPR is a powerful gene-editing technique first discovered in bacteria and adapted for permanent human gene knockout. While […]

Non Hormonal Birth Control Article Image

Development of an Effective Non-Hormonal Female Contraception

Birth control is a universal term that encompasses everything from a physical barrier to the chemical inhibition of ovulation. The most common form of contraception, according to the CDC, is female sterilization. Excluding sterilization, the second and third most common forms of birth control are oral contraceptive pills and long-acting reversible contraceptives. The commonality of […]

AstraZeneca closes mega $39B Alexion buyout despite antitrust fears, making a splash in rare diseases

AstraZeneca’s mega $39 billion takeover of Alexion Pharmaceuticals has come to a close, delivering the British pharma a lucrative portfolio of immunology medicines and a towering presence in rare diseases. AZ on Wednesday announced the completion of its Alexion acquisition, a week after securing a pivotal nod from the U.K.’s Competition and Markets Authority (CMA). Industry watchers were concerned […]