Obesity Leading to Preventable, Premature Death Obesity prevalence is the primary cause of metabolic issues that lead to preventable and premature death. The rate of obesity has increased since 2017 from 30.5% to 41.9%. Additionally, the rates of severe obesity have almost doubled from 4.7% to 9.2%, with an annual medical cost of approximately 173 […]
Transplanted Human Cortical Organoids One of the largest hurdles in the advancement of medicinal sciences is its applicability to heal or cure. Numerous strides have been made in order to close this gap by revolutionizing the mouse animal model. The ability of the animal to contain any human-derived cells or tissue used for therapeutic drug […]
Reprogramming of Adult Cells? Anti-aging research has been conducted for decades, very little progress has been made due to the vast complexities of the aging process. Many theories of aging have been proposed, as well as the development of large labs focused on longevity research such as Altos Labs funded by Jeff Bezos. Research surrounding […]
Psychedelics Show Promise for Mental Health Disorders Until recently, psychedelics, specifically psilocin from mushrooms and lysergic acid diethylamide (LSD), were limited to recreational use with no medicinal benefit. Currently, psychedelics are showing promise in clinical trials as therapeutic strategies for mental health disorders. While scientists understand the serotonergic modulation these drugs elicit in the brain […]
Promising Results Shown for CRISPR CRISPR has shown promising results in preliminary clinical studies to correct sickle cell disease and treat blindness, transthyretin amyloidosis, and hereditary angioedema. A new study in collaboration with University College London and Great Ormond Street Hospital for Children investigated the potential feasibility of base-edited CD7-targeted chimeric antigen receptor (BE-CAR7) T […]
Wetware, the integration of human and machine, computer and neuronal circuits combined seamlessly to enhance and control the electronic world around us; to some, it is the essence of science fiction. In 1995 Hollywood produced a dystopian cyberpunk spin on wetware with the release of Johnny Mnemonic, played by Keanu Reeves, and portrayed a […]
Prevent Deadly Heart Arrhythmias? Heart disease and the complications caused by heart disease is the number one killer in the United States. The Center for Disease Control reports that someone in the US dies of a heart attack every 40 seconds, and approximately 805,000 people in the US have a heart attack annually. While heart […]
Queen asked in their song of the same title “Who Wants to Live Forever?” Humanity has always struggled with its mortality. Everything ages from machinery to homes to organisms and people. However, Sinclair and LaPlante wrote, “There is no law of biology that says we must age at the rate at which we do now.” […]
Using AI to Solve the Misfolded Protein Riddle One of the most daunting challenges in drug discovery is finding drugs for proteins that misfold. The primary drug design objective is for a small drug molecules to be able to enter an active site and block an enzyme’s or ion channel’s normal function, inhibiting its action […]
New Method for Insulin Delivery Using Stem Cells There are many types of diabetes mellitus including juvenile-onset diabetes (type 1), adult-onset diabetes (type 2), and diabetes during pregnancy (gestational diabetes). The underlying mechanism of all diabetes is dysfunctional or non-existent excretion of insulin from the islet cells of the pancreas or insulin insensitivity at the […]